The introduction of artificial joints is one of the great successes in the history of medical research. The procedure is today a standardized procedure and it increases the patients quality of life dramatically. Nevertheless, 10-20% of the patients experience loosening of the prosthesis within a short period of time after the surgery, and ultimately, most prosthesis become loose.
Arthritis is a joint disorder that involves inflammation of one or more joints. The inflammation may be triggered by infections in the joint or by autoimmune processes. In many of the arthritic conditions, such as osteoarthritis, the cause and process of the disease are not well understood.
Molecular diagnostics is the analysis of small molecules, typically genetic material and proteins expressed in an organism, that correlate with a pathogenesis and therefore may be used as a marker of disease.